Topic

Symetries and asymetries of the immune system response: A categorification approach

Resource type
Authors/contributors
Title
Symetries and asymetries of the immune system response: A categorification approach
Abstract
A new modeling approach and conceptual framework to the immune system response and its dual role with respect to cancer is proposed based on Applied Category Theory. States of cells and pathogenes are structured as mathematical structures (categories), the interactions, at a given phase, between cells of the immune system and pathogenes, correspond to a pair of adjunctions (adjoint functors), the interaction process consisting of the sequential composition of an identification phase, a preparation phase and an activation phase is modeled by the composition of maps of adjunctions: the approach is illustrated by considering the Cancer-Immunity Cycle. A third dimension is needed to model Cancer Immunoediting. The categorical foundations of our approach is based on Marco Grandis and Rober Paré theory of Intercategories.
Date
November 2017
Proceedings Title
2017 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)
Conference Name
2017 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)
Pages
1451-1454
DOI
10/ggdnd3
Short Title
Symetries and asymetries of the immune system response
Library Catalog
IEEE Xplore
Extra
ZSCC: 0000000 ISSN: null
Citation
Mascari, J.-F., Giacchero, D., & Sfakianakis, N. (2017). Symetries and asymetries of the immune system response: A categorification approach. In 2017 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) (pp. 1451–1454). https://doi.org/10/ggdnd3
BIOLOGY, NEUROSCIENCE & PSYCHOLOGY
Methodology
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